Arizona’s season is collapsing as an organization, with the offense failing to meet the defense’s solid work and postseason odds fading. Key mistakes define the day: Demercado’s goal-line fumble after a 72-yard burst, Taylor-Demerson’s late interception fumble that bounced into the end zone, and Harrison Jr.’s early brilliance followed by a quiet second half. Coach and scheme questions loom as fans wonder where the turnaround might come from, and fantasy managers watch for signs of life amid the chaos.

Fantasy takeaway: the big-play potential remains, but volatility at QB, play-calling, and ball security dampen value. Harrison Jr. could rebound if involved more consistently; Demercado’s dynasty value hinges on goal-line usage and fumbles discipline; the defense remains a steady floor, but overall offense must stabilize to salvage fantasy opportunities.

Arizona’s Week 5 loss to Tennessee was a gut punch, built on a sequence of self-inflicted errors and a flood of penalties that doomed what looked like a potential breakout. The game opened with a sharp, high-flying offense, but eight flags and a string of critical mistakes flipped the script and handed the Titans a chance to steal it in the final seconds.

Kyler Murray connected on early drives with Harrison Jr. and the run game showed life, but the offense faded after the break as the Cardinals couldn’t sustain momentum or adjust to adversity. On the other side, Arizona’s defense pressured Cam Ward and held firm most of the day, even as the walk-off FG ended hopes for Week 6. The result leaves questions about coaching, ball security, and how the roster responds in the coming days.

The takeaway: the team has bright spots—Murray’s start, Harrison Jr.’s chemistry, a stout defensive push—but must clean nonnegotiables like ball security and discipline if they want to salvage the season. Week 6 looms as a critical test for the Cardinals’ adjustments and leadership under fire.

Arden Key's thigh injury could sideline the Titans’ top edge in Week 5 against the Cardinals, forcing Tennessee to navigate without a heavy pass-rush contributor. If he misses time, Jeffery Simmons must anchor even more, and the Titans’ edge depth will be tested as Kyler Murray eyes time in the pocket.

Key’s value to Tennessee’s defense has been highlighted by pundits like PFF’s Jonathon Macri, who calls him underrated and notes a 77.2 pass-rush grade since 2021. Tennessee flashed in the second half vs Arizona, but the offense lagged, leaving Cam Ward to spark late drives and the defense to hold the line in a race to its first win without Key.